Cellular mechanisms for cargo delivery and polarity maintenance at different polar domains in plant cells

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F16%3A00095599" target="_blank" >RIV/00216224:14740/16:00095599 - isvavai.cz</a>

Result on the web

<a href="https://www.nature.com/articles/celldisc201618" target="_blank" >https://www.nature.com/articles/celldisc201618</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/celldisc.2016.18" target="_blank" >10.1038/celldisc.2016.18</a>

Result language

angličtina

Original language name

Cellular mechanisms for cargo delivery and polarity maintenance at different polar domains in plant cells

Original language description

The asymmetric localization of proteins in the plasma membrane domains of eukaryotic cells is a fundamental manifestation of cell polarity that is central to multicellular organization and developmental patterning. In plants, the mechanisms underlying the polar localization of cargo proteins are still largely unknown and appear to be fundamentally distinct from those operating in mammals. Here, we present a systematic, quantitative comparative analysis of the polar delivery and subcellular localization of proteins that characterize distinct polar plasma membrane domains in plant cells. The combination of microscopic analyses and computational modeling revealed a mechanistic framework common to diverse polar cargos and underlying the establishment and maintenance of apical, basal, and lateral polar domains in plant cells. This mechanism depends on the polar secretion, constitutive endocytic recycling, and restricted lateral diffusion of cargos within the plasma membrane. Moreover, our observations suggest that polar cargo distribution involves the individual protein potential to form clusters within the plasma membrane and interact with the extracellular matrix. Our observations provide insights into the shared cellular mechanisms of polar cargo delivery and polarity maintenance in plant cells.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10601 - Cell biology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

CELL DISCOVERY

ISSN

2056-5968

e-ISSN

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Volume of the periodical

2

Issue of the periodical within the volume

JUL

Country of publishing house

GB - UNITED KINGDOM

Number of pages

18

Pages from-to

16018

UT code for WoS article

000414797400001

EID of the result in the Scopus database

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