MicroRNAs as a tool to aid stratification of colorectal cancer patients and to guide therapy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F17%3A00100447" target="_blank" >RIV/00216224:14740/17:00100447 - isvavai.cz</a>
Result on the web
<a href="https://www.futuremedicine.com/doi/10.2217/pgs-2017-0004" target="_blank" >https://www.futuremedicine.com/doi/10.2217/pgs-2017-0004</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2217/pgs-2017-0004" target="_blank" >10.2217/pgs-2017-0004</a>
Alternative languages
Result language
angličtina
Original language name
MicroRNAs as a tool to aid stratification of colorectal cancer patients and to guide therapy
Original language description
Colorectal cancer is a common type of malignant disease with high rates of morbidity and mortality. Although treatment options have been expanded over the last years, the mainstay of curative treatment remains surgical removal of the tumor-bearing organ. Systemic treatment options include classic cytotoxic drugs as well as some biological agents. Noncoding RNAs are an evolving field in cancer diagnosis, prognosis and possible treatment. Noncoding miRNAs are small molecules with huge impact on gene expression. They have been a substantial part of cancer research for more than a decade. In this review article, the current knowledge of miRNAs and colorectal cancer diagnosis, prognosis and novel or evolving therapeutic concepts are discussed. Examples of how miRNAs might change the management of the disease will be described.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PHARMACOGENOMICS
ISSN
1462-2416
e-ISSN
—
Volume of the periodical
18
Issue of the periodical within the volume
10
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
1027-1038
UT code for WoS article
000405697300010
EID of the result in the Scopus database
2-s2.0-85024490495