Influence of k-space trajectory corrections on proton density mapping with ultrashort echo time imaging: Application for imaging of short T2 components in white matter

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F18%3A00101216" target="_blank" >RIV/00216224:14740/18:00101216 - isvavai.cz</a>

Alternative codes found

RIV/68081731:_____/18:00491279 RIV/65269705:_____/18:00069532

Result on the web

<a href="http://dx.doi.org/10.1016/j.mri.2018.04.020" target="_blank" >http://dx.doi.org/10.1016/j.mri.2018.04.020</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mri.2018.04.020" target="_blank" >10.1016/j.mri.2018.04.020</a>

Result language

angličtina

Original language name

Influence of k-space trajectory corrections on proton density mapping with ultrashort echo time imaging: Application for imaging of short T2 components in white matter

Original language description

Purpose: To evaluate the impact of MR gradient system imperfections and limitations for the quantitative mapping of short T2* signals performed by ultrashort echo time (UTE) acquisition approach. Materials and methods: The measurement of short T2* signals from a phantom and a healthy volunteer study (8 subjects of average age 28 4 years) were performed on a 3T scanner. The characteristics of the gradient system were obtained using calibration method performed directly on the measured subject or phantom. This information was used to calculate the actual sampling trajectory with the help of a parametric eddy current model. The actual sample positions were used to reconstruct corrected images and compared with uncorrected data. Results: Comparison of both approaches, i.e., without and with correction of k-space sampling trajectories revealed substantial improvement when correction was applied. The phantom experiments demonstrate substantial in-plane signal intensity variations for uncorrected sampling trajectories. In the case of the volunteer study, this led to significant differences in relative proton density (RPD) estimation between the uncorrected and corrected data (P = 0.0117 by Wilcoxon matched-pairs test) and provides for about 15% higher values for short T2* components of white matter (WM) in the case of uncorrected images. Conclusion: The imperfection of the applied gradients could induce errors in k-space data sampling which further propagates into the fidelity of the UTE images and jeopardizes precision of quantification. However, the study proved that measurement of gradient errors together with correction of sample positions can contribute to increased accuracy and unbiased characterization of short T2* signals.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

MAGNETIC RESONANCE IMAGING

ISSN

0730-725X

e-ISSN

—

Volume of the periodical

51

Issue of the periodical within the volume

SEP

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

87-95

UT code for WoS article

000437819200012

EID of the result in the Scopus database

2-s2.0-85046688616