Detection of a deletion at 22q11 locus involving ZNF280A/ZNF280B/PRAME/GGTLC2 in B-cell malignancies: simply a consequence of an immunoglobulin lambda light chain rearrangement
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F19%3A00108506" target="_blank" >RIV/00216224:14740/19:00108506 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/19:00071136
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.15922" target="_blank" >https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.15922</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/bjh.15922" target="_blank" >10.1111/bjh.15922</a>
Alternative languages
Result language
angličtina
Original language name
Detection of a deletion at 22q11 locus involving ZNF280A/ZNF280B/PRAME/GGTLC2 in B-cell malignancies: simply a consequence of an immunoglobulin lambda light chain rearrangement
Original language description
In this journal, Mestichelli et al (2018) recently reported that a submicroscopic 22q11 deletion is a potentially significant genomic aberration in chronic lymphocytic leukaemia (CLL), and that this alteration is missed by current routine techniques. This was based on the analysis of 23 CLL cases by oligonucleotide-based array comparative genomic hybridisation (aCGH; CytoChipCancer 4x180K, Illumina). The authors found 4 CLL cases with a deletion located at 22q11 that ranged in size from 0.68 Mb–0.49 Mb. The authors claimed that the minimally deleted region included the ZNF280A, ZNF280B, GGTLC2 and PRAME genes. The deletion in the 22q11 region was originally described by Gunn et al (2009) using aCGH and detected in 28 out of 187 analysed CLL cases.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30205 - Hematology
Result continuities
Project
<a href="/en/project/NV18-03-00054" target="_blank" >NV18-03-00054: THE ROLE OF MICRORNAS AND THEIR TARGETS IN THE TRANSFORMATION OF FOLLICULAR LYMPHOMA AND AGGRESSIVENESS OF CHRONIC LYMPHOCYTIC LEUKEMIA</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
British journal of haematology
ISSN
0007-1048
e-ISSN
—
Volume of the periodical
186
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
„E91“-„E94“
UT code for WoS article
000478608100010
EID of the result in the Scopus database
2-s2.0-85064496995