Investigation of microRNA expression profiles related tomorphological heterogeneity in triple-negative breast cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F19%3A00108611" target="_blank" >RIV/00216224:14740/19:00108611 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Investigation of microRNA expression profiles related tomorphological heterogeneity in triple-negative breast cancer
Original language description
: Triple-negative breast cancers (TNBCs) are morphologically a heterogeneous group of breast carcinomas with no or minimal hormone receptor and HER2 protein expression or gene amplification. Due to its aggressive nature, novel therapeutic targets are urgently required to improve pathological complete response and clinical outcomes. In tumours, microRNAs (miRs) exhibit both oncogenic and tumour-supressor function. The aim of this study was to indentify a possible association between miRs expression profile and intratumoural morphology within different samples of TNBC.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
<a href="/en/project/NV16-31997A" target="_blank" >NV16-31997A: Diagnostic and prognostic impact of miRNA expression profiles related to morphological heterogeneity in triple-negative breast cancer</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů