The H3 histone chaperone NASP(SIM3) escorts CenH3 in Arabidopsis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F20%3A00120575" target="_blank" >RIV/00216224:14740/20:00120575 - isvavai.cz</a>
Alternative codes found
RIV/61389030:_____/20:00523294
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/tpj.14518" target="_blank" >https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/tpj.14518</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/tpj.14518" target="_blank" >10.1111/tpj.14518</a>
Alternative languages
Result language
angličtina
Original language name
The H3 histone chaperone NASP(SIM3) escorts CenH3 in Arabidopsis
Original language description
Centromeres define the chromosomal position where kinetochores form to link the chromosome to microtubules during mitosis and meiosis. Centromere identity is determined by incorporation of a specific histone H3 variant termed CenH3. As for other histones, escort and deposition of CenH3 must be ensured by histone chaperones, which handle the non-nucleosomal CenH3 pool and replenish CenH3 chromatin in dividing cells. Here, we show that the Arabidopsis orthologue of the mammalian NUCLEAR AUTOANTIGENIC SPERM PROTEIN (NASP) and Schizosaccharomyces pombe histone chaperone Sim3 is a soluble nuclear protein that binds the histone variant CenH3 and affects its abundance at the centromeres. NASP(SIM3) is co-expressed with Arabidopsis CenH3 in dividing cells and binds directly to both the N-terminal tail and the histone fold domain of non-nucleosomal CenH3. Reduced NASP(SIM3) expression negatively affects CenH3 deposition, identifying NASP(SIM3) as a CenH3 histone chaperone.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10611 - Plant sciences, botany
Result continuities
Project
<a href="/en/project/EF17_050%2F0008496" target="_blank" >EF17_050/0008496: MSCAfellow@MUNI</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Plant Journal
ISSN
0960-7412
e-ISSN
—
Volume of the periodical
101
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
16
Pages from-to
71-86
UT code for WoS article
000490775400001
EID of the result in the Scopus database
2-s2.0-85074251001