Dynamic functional connectivity in prodromal dementia with Lewy body

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F22%3A00139935" target="_blank" >RIV/00216224:14740/22:00139935 - isvavai.cz</a>
Result on the web
<a href="http://aktion.workplace.cz/DZS/Aktion.nsf/eed8105c5c90ad4ec1256c8e00458071/dce7ad13c97ba410c125883600550171/$FILE/FinalReportAKTION2022_MKDJ.pdf" target="_blank" >http://aktion.workplace.cz/DZS/Aktion.nsf/eed8105c5c90ad4ec1256c8e00458071/dce7ad13c97ba410c125883600550171/$FILE/FinalReportAKTION2022_MKDJ.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Dynamic functional connectivity in prodromal dementia with Lewy body
Original language description
In this work, we analyzed dynamic functional connectivity in 56 subjects (25 healthy controls and 31 MCI-LB) in order to detect changes related to early signs of neurodegeneration in the fMRI in brain states related to preparation to the action. We used method called sliding window analysis. We found significant differences in dwell time in one of 4 identified brain states. This dwell time significantly correlated with visuospatial memory in MCI-LB group whereas in HC group was no significant correlation present. Observed changes probably reflect compensatory mechanisms of MCI-LB.
Czech name
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Czech description
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Project
<a href="/en/project/NU21J-04-00077" target="_blank" >NU21J-04-00077: Biomarkers of neurodegenerative diseases based on dynamic functional connectivity</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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