Palaeoproteomics of Dental Calculus: Exploring the Biomolecular Archive
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F25%3A00142334" target="_blank" >RIV/00216224:14740/25:00142334 - isvavai.cz</a>
Result on the web
<a href="https://www.ceitec.eu/2025-ceitec-iocb-symposium-for-early-career-researchers/a5312" target="_blank" >https://www.ceitec.eu/2025-ceitec-iocb-symposium-for-early-career-researchers/a5312</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Palaeoproteomics of Dental Calculus: Exploring the Biomolecular Archive
Original language description
Dental calculus, a calcified form of dental plaque, entraps and preserves a wide range of particles that enter the oral cavity during life. As a rich source of information, dental calculus has become a focal point in biomolecular archaeology, greatly expanding our understanding of past populations. Biomolecular research has revealed insights into the ancient oral microbiome, respiratory and oral pathogens, diet, habitual practices, identity and migration, as well as medicinal use of plants. In our project, we applied palaeoproteomic approaches to characterize the complex protein composition of ancient dental calculus. Samples originated from individuals buried at sites representing diverse geographical and temporal contexts. The most relevant and unique findings included plant-derived proteins with potential dietary or medicinal significance, together with numerous bacterial taxa, including putative pathogens. These results emphasize the potential of palaeoproteomics to unlock biomolecular information from dental calculus, demonstrating its value as a unique archive for reconstructing health, diet, and cultural practices in past populations.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů