Synthesis and Characterisation of a New Amphotericin B-Methoxypoly(ethylene Glycol) Conjugate
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F01%3A00000100" target="_blank" >RIV/00216275:25310/01:00000100 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Synthesis and Characterisation of a New Amphotericin B-Methoxypoly(ethylene Glycol) Conjugate
Original language description
The reaction of methoxypoly(ethylene glycol)-4-nitrophenyl carbonate with amphotericin B has been used to prepare a new conjugate of amphotericin B (mPEG-AmB). A preliminary screening of in vitro antifugal activity has suggested that mPEG-AmB possees a similar effect and a similar spectrum of activity as the conventional amphotericin B formulated with sodium desoxycholate.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2001
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bioorganic & Medicinal Chemistry Letters
ISSN
0960-894X
e-ISSN
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Volume of the periodical
11
Issue of the periodical within the volume
Listopad
Country of publishing house
GB - UNITED KINGDOM
Number of pages
3
Pages from-to
2833-2835
UT code for WoS article
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EID of the result in the Scopus database
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