Precision Limits and Interval Estimation in the Calibration of 1-hydroxypyrene in Urine and Hexachlorbenzene in Water, Applying theRegression Triplet Procedure on Chromatographic Data
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F08%3A00006024" target="_blank" >RIV/00216275:25310/08:00006024 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Precision Limits and Interval Estimation in the Calibration of 1-hydroxypyrene in Urine and Hexachlorbenzene in Water, Applying theRegression Triplet Procedure on Chromatographic Data
Original language description
A method for the determination of 1-hydroxypyrene in urine and hexychlorbenzene in water applying the regression triplet in the calibration procedure of chromatographic data has been applied using the program QCEXPERT. The detection limit and quantification limit are currently calculated on the basis of the standard deviation of replicate analyses at a single concentration. However, since the standard deviation depends on concentration, these single concentration techniques result in limits that are directly dependent on spiking concentration. A more rigorous approach requires at first careful attention to the three components of the regression triplet (data, model, method), examining (a) the data quality of the proposed model; (b) the model quality; (c) the LS method to be used for a fulfilment of all least squares assumptions. On HPLC determination of 1-hydroxypyrene in urine and gas chromatography analysis of hexachlorbenzene in water, this paper describes the effects of deviations
Czech name
Limity přesnosti a intervalové odhady v kalibraci 1-hydroxypyrenu v moči a hexachlorbenzenu ve vodě aplikací regresního tripletu na chromatografická data
Czech description
Limity přesnosti a intervalové odhady při kalibraci 1-hydroxypyrenu v moči a hexachlorbenzenu ve vodě aplikací regresního tripletu na chromatografická data byly provedeny programem QCEXPERT. Limita detekce a limita kvantifikace spolu s kritickou urovní byly vyhodnoceny na základě opakovaných meření v kalibračním grafu. Kalibrační graf byl analyzován lineární regresí s využitím regresního tripletu (kritika dat, kritika modelu a kritika metody). Ukázalo se, že odlehlé hodnoty kalibračního grafu silně ovlivňují limitu detekce a intervalový odhad neznámé koncentrace ve vzorku a je třeba jim proto věnovat pozornost.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NR9055" target="_blank" >NR9055: Influence of smoking and its cessation on endocrine system</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2008
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Analytical and Bioanalytical Chemistry
ISSN
1618-2642
e-ISSN
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Volume of the periodical
390
Issue of the periodical within the volume
7
Country of publishing house
DE - GERMANY
Number of pages
12
Pages from-to
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UT code for WoS article
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EID of the result in the Scopus database
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