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Efficient Synthesis of 5-(2-Hydroxyethyl)-2-phenylimino-1,3-thiazolidin-4-ones and 5-(2-Hydroxyethyl)-2-phenylamino-4,5-dihydro-1,3-thiazol-4-ones

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F09%3A00008315" target="_blank" >RIV/00216275:25310/09:00008315 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Efficient Synthesis of 5-(2-Hydroxyethyl)-2-phenylimino-1,3-thiazolidin-4-ones and 5-(2-Hydroxyethyl)-2-phenylamino-4,5-dihydro-1,3-thiazol-4-ones

  • Original language description

    A new method for the synthesis of substituted 5-(2-hydroxyethyl)-2-phenylimino-1,3-thiazolidin-4- ones and 5-(2-hydroxyethyl)-2-phenylamino-4,5-dihydro-1,3-thiazol-4-ones is described, starting from phenylthioureas and 3-bromotetrahydrofuran-2-one. The reaction proceeds under mild conditions, is very simple to perform, and is applicable to a relatively wide range of substituents in benzene nucleus. Some 1,3-thiazolidin-4-ones show dynamic NMR behavior in solution because of prototropy tautomerism and E/Z-stereoisomerism.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Heterocyclic Chemistry

  • ISSN

    0022-152X

  • e-ISSN

  • Volume of the periodical

    46

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    5

  • Pages from-to

  • UT code for WoS article

  • EID of the result in the Scopus database