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Miminizing the Effects of Multicollinearity in the Polynomial Regression of Age Relationships and Sex Differences in Serum Levels of Pregnelonone Sulfate in Healthy Subjects

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F09%3A00008380" target="_blank" >RIV/00216275:25310/09:00008380 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Miminizing the Effects of Multicollinearity in the Polynomial Regression of Age Relationships and Sex Differences in Serum Levels of Pregnelonone Sulfate in Healthy Subjects

  • Original language description

    Pregnenolone-sulfate (PregS) is known as a steroid conjugate positively modulating N-methyl-D-aspartate (NMDA) receptors on neuronal membranes. These receptors are responsible for permeability of calcium channels and activation of neuronal function. Neuroactivating effect of PregS is also exerted via noncompetitive negative modulation of GABAA receptors regulating the chloride influx. Recently, a penetrability of blood-brain barrier for PregS was found in rat, but some experiments being in agreement with this finding were reported even beforehand.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Clinical Chemistry and Laboratory Medicine

  • ISSN

    1434-6621

  • e-ISSN

  • Volume of the periodical

    47

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    7

  • Pages from-to

  • UT code for WoS article

  • EID of the result in the Scopus database