Microfluidic system with integrated magnetic carrier for immunoprecipitation of Abeta peptides

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F09%3A00008575" target="_blank" >RIV/00216275:25310/09:00008575 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Microfluidic system with integrated magnetic carrier for immunoprecipitation of Abeta peptides
Original language description
Alzheimer disease (AD) is the most prevalent cause of dementia in the elderly population today with an increasing tendency. In spite of the fact that it is so common, AD often goes unrecognized or is misdiagnosed in its early stages. The importance of the early and accurate diagnosis is evident. Development of valuable diagnostic methods for determination of AD specific biomarkers, such as Abeta peptides and Tau protein, is one of the current goals. The aim of this study is integration of immunomagneticcarrier with orientedly immobilized anti-A? antibody into microfluidic device and an application of this system for immunoprecipitation of Abeta peptides. Binding efficiency and specificity of the immunosorbent were validated by serum or cerebrospinal fluid spiked with synthetic Abeta peptides.
Czech name
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Czech description
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Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
New Trends in Alzheimer and Parkinson Related Disorders: ADPD 2009
ISBN
978-88-7587-528-2
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
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Publisher name
MEDIMOND s.r.l.
Place of publication
Pianoro
Event location
Praha
Event date
Mar 15, 2009
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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