Eco-Synthesis of PVA/Chitosan Hydrogels for Biomedical Application
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F11%3A39892342" target="_blank" >RIV/00216275:25310/11:39892342 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s10924-011-0334-0" target="_blank" >http://dx.doi.org/10.1007/s10924-011-0334-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10924-011-0334-0" target="_blank" >10.1007/s10924-011-0334-0</a>
Alternative languages
Result language
angličtina
Original language name
Eco-Synthesis of PVA/Chitosan Hydrogels for Biomedical Application
Original language description
A drug delivery system based on physically cross-linked poly vinyl alcohol (PVA)/chitosan blend hydrogels for the release of sparfloxacin antibiotic as a model for drugs was described. Eco-synthesis in current work is based on synthesizing a hydrogel without using chemical crosslinking agents like in the conventional method. In addition all materials are used are non- toxic, safe, non-carcinogenic and can be accepted by the human body without danger. The swelling behavior was tested to be dependent on pH as temperature as well as time and number of freezing thawing cycles. The physical properties of the hydrogels, such as swelling percent, dissolution percent, gel fraction and mechanical properties was assessed. The antimicrobial activity of hydrogelshaving different compositions was evaluated for both gram positive and gram negative bacteria. Furthermore, the release of antibiotic from hydrogels prepared using the freeze- thawed process was studied.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Polymers and the Environment
ISSN
1566-2543
e-ISSN
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Volume of the periodical
19
Issue of the periodical within the volume
4
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
1005-1012
UT code for WoS article
000297370100022
EID of the result in the Scopus database
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