Recent Advances in the Design of Organic Polymer Monoliths for Reversed-Phase and Hydrophilic Interaction Chromatography Separations of Small Molecules

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F13%3A39896428" target="_blank" >RIV/00216275:25310/13:39896428 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs00216-012-6392-x" target="_blank" >http://link.springer.com/article/10.1007%2Fs00216-012-6392-x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00216-012-6392-x" target="_blank" >10.1007/s00216-012-6392-x</a>

Result language
angličtina
Original language name
Recent Advances in the Design of Organic Polymer Monoliths for Reversed-Phase and Hydrophilic Interaction Chromatography Separations of Small Molecules
Original language description
Owing to their favorable porous structure with pore size distribution shifted towards large flow-through pores, organic polymer monoliths have been mainly employed for the separation of macromolecules in gradient elution liquid chromatography. The absence of significant amounts of small pores with a stagnant mobile phase and the resulting low surface area were considered as the main reason for their poor behavior in the isocratic separation of small molecules. Several recent efforts have improved the separation power of organic polymer monoliths for small molecules offering column efficiency up to tens of thousands of plates per meter. These attempts include optimization of the composition of polymerization mixture, including the variation of functional monomer, the cross-linking monomer, and the porogen solvents mixture, adjustment of polymerization temperature, and time. Additionally, post-polymerization modifications including hypercross-linking and the use of carbon nanostructures
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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