Determination and Detailed Mechanism Study of Antiviral Drug Fosamprenavir Using Carbon Paste Electrode in the Presence of Triton X-100
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F13%3A39896534" target="_blank" >RIV/00216275:25310/13:39896534 - isvavai.cz</a>
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0013468613013698" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0013468613013698</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.electacta.2013.07.100" target="_blank" >10.1016/j.electacta.2013.07.100</a>
Alternative languages
Result language
angličtina
Original language name
Determination and Detailed Mechanism Study of Antiviral Drug Fosamprenavir Using Carbon Paste Electrode in the Presence of Triton X-100
Original language description
The detailed electrochemical oxidation and selective determination of fosamprenavir were studied in aqueous-alcohol medium at a carbon paste electrode. Electrochemical behavior of fosamprenavir was investigated as details by different electrochemical techniques in the absence and presence of Triton X-100. The electrochemical mechanism was also carried out and aromatic amine part of the molecule was found to be involved in electrochemical oxidation of fosamprenavir. The oxidized form takes part in hydrolysis; the products are also electroactive and participate in redox reaction. Voltammetric studies were realized between pH 1.0 and 12.0. In the presence of Triton X-100, the signal increased almost 5 times. The promising analytical performance was obtained with developed method. A systematic study of the experimental parameters such as pH, scan rate, accumulation potential and accumulation time that affect the square wave stripping response was carried out and the optimized experimental
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CG - Electrochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/EE2.3.30.0021" target="_blank" >EE2.3.30.0021: Strenthening of Research and Development Teams at the University of Pardubice</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrochimica Acta
ISSN
0013-4686
e-ISSN
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Volume of the periodical
109
Issue of the periodical within the volume
říjen
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
381-388
UT code for WoS article
000328006300054
EID of the result in the Scopus database
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