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Determination and Detailed Mechanism Study of Antiviral Drug Fosamprenavir Using Carbon Paste Electrode in the Presence of Triton X-100

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F13%3A39896534" target="_blank" >RIV/00216275:25310/13:39896534 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.sciencedirect.com/science/article/pii/S0013468613013698" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0013468613013698</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.electacta.2013.07.100" target="_blank" >10.1016/j.electacta.2013.07.100</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Determination and Detailed Mechanism Study of Antiviral Drug Fosamprenavir Using Carbon Paste Electrode in the Presence of Triton X-100

  • Original language description

    The detailed electrochemical oxidation and selective determination of fosamprenavir were studied in aqueous-alcohol medium at a carbon paste electrode. Electrochemical behavior of fosamprenavir was investigated as details by different electrochemical techniques in the absence and presence of Triton X-100. The electrochemical mechanism was also carried out and aromatic amine part of the molecule was found to be involved in electrochemical oxidation of fosamprenavir. The oxidized form takes part in hydrolysis; the products are also electroactive and participate in redox reaction. Voltammetric studies were realized between pH 1.0 and 12.0. In the presence of Triton X-100, the signal increased almost 5 times. The promising analytical performance was obtained with developed method. A systematic study of the experimental parameters such as pH, scan rate, accumulation potential and accumulation time that affect the square wave stripping response was carried out and the optimized experimental

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CG - Electrochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/EE2.3.30.0021" target="_blank" >EE2.3.30.0021: Strenthening of Research and Development Teams at the University of Pardubice</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Electrochimica Acta

  • ISSN

    0013-4686

  • e-ISSN

  • Volume of the periodical

    109

  • Issue of the periodical within the volume

    říjen

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    381-388

  • UT code for WoS article

    000328006300054

  • EID of the result in the Scopus database