Polystyrene copolymer-supported by substituted (1R,2R)-1,2-diphenylethane-1,2-diamine-copper(II) complexes: recyclable catalyst for the asymmetric Henry reaction
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F14%3A39897793" target="_blank" >RIV/00216275:25310/14:39897793 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.tetasy.2014.04.004" target="_blank" >http://dx.doi.org/10.1016/j.tetasy.2014.04.004</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.tetasy.2014.04.004" target="_blank" >10.1016/j.tetasy.2014.04.004</a>
Alternative languages
Result language
angličtina
Original language name
Polystyrene copolymer-supported by substituted (1R,2R)-1,2-diphenylethane-1,2-diamine-copper(II) complexes: recyclable catalyst for the asymmetric Henry reaction
Original language description
Herein described the preparation of swelling pearl-like copolymer styrene-4-vinylbenzyl chloride crosslinked by means of tetra(ethylene glycol)-bis(4-vinylbenzyl)ether (200-800 mým). The pearl-like polymer was used to anchor (1R,2R)-1-amino-2-(2,3-dihydro-1H-isoindole-2-yl)-1,2-diphenylethane by a covalent bond; the product was subsequently transformed into the corresponding complex with Cu(II) acetate. The synthesized catalyst was used for the catalysis of the Henry reaction of functionalized aldehydeswith nitromethane in ethanol. The reactions proceeded in a polymeric matrix of the swelling catalyst at a rate comparable with the rates of reactions in a homogeneous medium. The corresponding functionalized 2-nitroethanols were formed in quantitative yields (20 °C, 24 h) with enantiomeric excess values of up to 96%. The catalyst was recycled five times without losing its effectiveness with regard to the yield and enantioselectivity; only a partial mechanical degradation of the polymeri
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA14-00925S" target="_blank" >GA14-00925S: Immobilized Enantioselective Catalysts</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Tetrahedron Asymmetry
ISSN
0957-4166
e-ISSN
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Volume of the periodical
25
Issue of the periodical within the volume
9
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
6
Pages from-to
775-780
UT code for WoS article
000336879400010
EID of the result in the Scopus database
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