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Degradation study of nitroaromatic explosives 2-diazo-4,6-dinitrophenol and picramic acid using HPLC and UHPLC-ESI-MS/MS

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F14%3A39898721" target="_blank" >RIV/00216275:25310/14:39898721 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11160/14:10281874

  • Result on the web

    <a href="http://dx.doi.org/10.1039/c4ay00401a" target="_blank" >http://dx.doi.org/10.1039/c4ay00401a</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1039/c4ay00401a" target="_blank" >10.1039/c4ay00401a</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Degradation study of nitroaromatic explosives 2-diazo-4,6-dinitrophenol and picramic acid using HPLC and UHPLC-ESI-MS/MS

  • Original language description

    A new and fast HPLC method with UV detection was developed and validated for the simultaneous determination of nitroaromatic explosives diazodinitrophenol (DDNP), the raw material picramic acid (PicA) and three degradation products of DDNP. DDNP and PicAwere subjected to forced degradation. DDNP was found to be stable under acidic and basic conditions, while thermal, oxidative and photolytic decomposition resulted in three degradation products. Degradation products were separated from DDNP using Ascentis(R) Express C18 fused core particle column and subsequently characterised using UHPLC-ESI-MS/MS method. Optimal chromatography was performed using the isocratic elution of mobile phase consisting of acetonitrile-orthophosphoric acid 0.085% 30 : 70 (v/v) pumped at a flow rate of 0.8 mL/min at a temperature of 50°C. System suitability test parameters, linearity and precision of the HPLC method were evaluated. The new HPLC method is suitable for a fast determination of DDNP and degradatio

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Analytical Methods

  • ISSN

    1759-9660

  • e-ISSN

  • Volume of the periodical

    6

  • Issue of the periodical within the volume

    13

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    4761-4768

  • UT code for WoS article

    000337763200041

  • EID of the result in the Scopus database