Comparison of Selected Matrices, Nanostructures and Other Materials in (MA)LDI Analysis of Lipids
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F14%3A39899341" target="_blank" >RIV/00216275:25310/14:39899341 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Comparison of Selected Matrices, Nanostructures and Other Materials in (MA)LDI Analysis of Lipids
Original language description
In our work, selected matrices, silver nanostructures and other metallic or non-metallic surfaces were compared with the aim to test their suitability for (MA)LDI-MS analysis of lipids in both polarity modes. The mixture of 25 representatives of lipid classes including acylglycerols, phospholipids, sterols, sphingolipids, glycosphingolipids was used for this comparison. Individual materials and matrices were scored with respect to the intensity of extracted ion currents of lipid molecular adducts. The effect of laser energy on the signal intensity was also studied and optimized value was used for final measurements. Non-metallic surfaces have not provided any signal of lipids, while some metallic materials have shown comparable or even better results to classical matrix approaches.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů