PHOTOCATALYTIC OXIDATION OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F16%3A39901704" target="_blank" >RIV/00216275:25310/16:39901704 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

PHOTOCATALYTIC OXIDATION OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS

Original language description

Pharmaceuticals diclofenac and naproxen belong to class of non-steroidal anti-inflammatory drugs (NSAIDs). These substances are very often found in outlets of WWTP or in surface waters, because among all classes of pharmaceuticals, they are frequently prescribed and purchased. These substances have by their nature a strong biological effect, so non-target organisms are affected. For example diclofenac causes cytological malformations of liver tissue within a concentration 28 ?g/L (O. mykkis). Sensitive organisms to naproxen are crustaceans, where the EC50 for (C. dubia) is 330 ?g/L, but degradation products of this drug are significantly more toxic. EC50 for degradation products of naproxen to C. dubia are less than 100 ?g/L. Diclofenac and naproxen (500 ?g/L) were from model water samples removed by heterogeneous photocatalysis in 4L batch reactor. After irradiation of the catalyst, the system produces .OH radicals, which causes destruction of the organic substance. As the catalyst used was 0.5 g/L titanium dioxide (TiO2, Precheza a.s.). As a source of UV radiation was used UV LED diode Luminus, with peak wavelength at 365 nm. At the same time the effect of hydrogen peroxide (H2O2) or effect of pH was determined. Samples were preconcentrated by solid phase extraction (SPE) and analyzed by high performance liquid chromatography (HPLC). At the same time characteristics and capability of pharmaceutical removal from inlet of WWTP were discussed.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

CI - Industrial chemistry and chemical engineering

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Proceedings of the 4th International Conference on Chemical Technology

ISBN

978-80-86238-94-4

ISSN

2336-811X

e-ISSN

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Number of pages

5

Pages from-to

440-444

Publisher name

Česká společnost průmyslové chemie

Place of publication

Praha

Event location

Mikulov

Event date

Apr 25, 2016

Type of event by nationality

EUR - Evropská akce

UT code for WoS article

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