Voltammetric determination of mesalazine in pharmaceutical preparations and biological samples using boron-doped diamond electrode

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F17%3A39910930" target="_blank" >RIV/00216275:25310/17:39910930 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s11696-017-0135-6" target="_blank" >http://dx.doi.org/10.1007/s11696-017-0135-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11696-017-0135-6" target="_blank" >10.1007/s11696-017-0135-6</a>

Result language

angličtina

Original language name

Voltammetric determination of mesalazine in pharmaceutical preparations and biological samples using boron-doped diamond electrode

Original language description

Voltammetric method for the determination of non-steroidal anti-inflammatory drug mesalazine (5-ASA) is presented for the first time using boron-doped diamond electrode (BDDE). 5-ASA provides one well-developed SWV oxidation peak at about -900 mV (vs. saturated silver/silver chloride reference electrode) on BDDE. Britton-Robinson buffer (pH 7.0) was chosen as an optimal supporting electrolyte for the determination of 5-ASA using square wave voltammetry (SWV). Parameters of SWV were developed and low limit of detection (7.0 9 10-7 mol L-1) was reached. In addition, relative standard deviation of repeated measurements (c5-ASA = 5 9 10-5 mol L-1, RSDM = 2.7%) and relative standard deviation of repeated determinations (RSDD 1.5%) were calculated and confirm obtained good results. Applicability of the proposed method was verified by an analysis of a pharmaceutical preparation and spiked human urine.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10406 - Analytical chemistry

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemical Papers

ISSN

0366-6352

e-ISSN

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Volume of the periodical

71

Issue of the periodical within the volume

8

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

1419-1427

UT code for WoS article

000405694900005

EID of the result in the Scopus database

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