Water-insoluble fibres, threads, and fabrics from lauroyl derivatives of hyaluronan

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F23%3A39920872" target="_blank" >RIV/00216275:25310/23:39920872 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0141813023005470?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0141813023005470?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ijbiomac.2023.123654" target="_blank" >10.1016/j.ijbiomac.2023.123654</a>

Result language
angličtina
Original language name
Water-insoluble fibres, threads, and fabrics from lauroyl derivatives of hyaluronan
Original language description
Hyaluronan (HA) is a naturally occurring polysaccharide widely used in medicine and cosmetics. To further broaden its potential, various HA derivatives have been developed with the aim of reducing solubility, slowing degradation, or providing other beneficial properties. However, for most medical applications, these derivatives must be processed into suitable forms. Here we present water-insoluble fibres prepared from lauroyl-modified HA using a wet spinning process. Important properties of the fibres, such as swelling or the degradation rate, can be fine-tuned by adjusting the degree of HA modification. Due to their mechanical properties, the lauroyl HA fibres can be easily processed into threads and subsequently into fabrics of various sizes, shapes, and degrees of porosity. In addition, in vitro cytotoxicity testing of the fibres showed that they were non-cytotoxic. Overall, our results suggest that lauroyl HA fibres are a promising material that could be used to develop a variety of medical devices.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10404 - Polymer science

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)