Enhancement of biocompatibility of anodic nanotube structures on biomedical Ti–6Al–4V alloy via ultrathin TiO2 coatings
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F24%3A39921853" target="_blank" >RIV/00216275:25310/24:39921853 - isvavai.cz</a>
Result on the web
<a href="https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2024.1515810/full" target="_blank" >https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2024.1515810/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fbioe.2024.1515810" target="_blank" >10.3389/fbioe.2024.1515810</a>
Alternative languages
Result language
angličtina
Original language name
Enhancement of biocompatibility of anodic nanotube structures on biomedical Ti–6Al–4V alloy via ultrathin TiO2 coatings
Original language description
This work aims to describe the effect of the surface modification of TiO2nanotube (TNT) layers on Ti-6Al-4V (TiAlV) alloy by ultrathin TiO2 coatingsprepared via Atomic Layer Deposition (ALD) on the growth of MG-63osteoblastic cells. The TNT layers with two distinctly different inner diameters,namely ~15 nm and ~50 nm, were prepared via anodic oxidation of the TiAlV alloy.Flat, i.e., non-anodized, TiAlV alloy foils were used as reference substrates.Additionally, a part of the TNT layers and alloy foils was coated with ultrathincoatings of TiO2 by ALD. The number of TiO2 ALD cycles used was 1 and 5 leadingto a nominal TiO2 thickness of ~0.055 and ~0.3 nm, respectively. The ultrathinTiO2 coating by ALD enabled to optimize the surface hydrophilicity for optimalcell growth. In addition, coatings shaded impurities of V- and F-based species(stemming from the alloy and the anodization electrolyte) that affect thebiocompatibility of the tested materials while preserving the original structureand morphology. The evaluation of the biocompatibility before and after TiO2ALD coating on TiAlV flat surfaces and TNT layers was carried out using MG-63osteoblastic cells and compared after incubation for up to 96 h. The cell growth,adhesion, and proliferation of the MG-63 on TiAlV foils and TNT layers showedsignificant enhancement after the surface modification by TiO2 ALD.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20506 - Coating and films
Result continuities
Project
<a href="/en/project/EF17_048%2F0007421" target="_blank" >EF17_048/0007421: Strengthening interdisciplinary cooperation in research of nanomaterials and their effects on living organisms (NANOBIO)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Bioengineering and Biotechnology
ISSN
2296-4185
e-ISSN
2296-4185
Volume of the periodical
12
Issue of the periodical within the volume
December
Country of publishing house
CH - SWITZERLAND
Number of pages
10
Pages from-to
1515810
UT code for WoS article
001378695000001
EID of the result in the Scopus database
2-s2.0-85212076032