EXPERIMENTAL STUDY OF AEROSOL DEPOSITION IN A REALISTIC MODEL OF THE LUNG

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F10%3APU87260" target="_blank" >RIV/00216305:26210/10:PU87260 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
EXPERIMENTAL STUDY OF AEROSOL DEPOSITION IN A REALISTIC MODEL OF THE LUNG
Original language description
The inhalation route for administration of medicaments is becoming more and more popular in recent years. The reason is non-invasiveness of the method and instantaneous absorption of drugs to the blood circulation. It is necessary to deliver exact amountof drug to the specific segment because of occurrence of diverse diseases in different segments of lungs. The aim of our work is to contribute to better understanding of transport and deposition of aerosolized drugs in lungs and hence to more effectivetreatment of respiratory diseases due to the targeted drug delivery. We provided measurements of aerosol deposition in segmented realistic model of lungs without a mouth cavity. Monodisperse particles marked with fluorescein were supplied to the model. The model was then disassembled to segments and each segment was rinsed with isopropanol, whereby fluorescent samples were created. Each sample was analysed by fluorometer and an amount of aerosol deposited in the segment was calculated. E
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
S - Specificky vyzkum na vysokych skolach

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
XXIX. mezinárodní konference Setkání kateder mechaniky tekutin a termomechaniky
ISBN
978-80-248-2244-0
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
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Publisher name
VŠB - TU Ostrava
Place of publication
Rožnov pod Radhoštěm
Event location
Rožnov pod Radhoštěm
Event date
Jun 23, 2010
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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