Effect of Hyaluronic Acid on Friction of Articular Cartilage

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F18%3APU128557" target="_blank" >RIV/00216305:26210/18:PU128557 - isvavai.cz</a>
Result on the web
<a href="http://www.engmech.cz/improc/2018/709.pdf" target="_blank" >http://www.engmech.cz/improc/2018/709.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.21495/91-8-709" target="_blank" >10.21495/91-8-709</a>

Result language
angličtina
Original language name
Effect of Hyaluronic Acid on Friction of Articular Cartilage
Original language description
Intra-articular injections of hyaluronic acid based solutions are gaining popularity as a treatment option for non-operative management of patients with degenerative joint diseases. Although there is a plenty of evidence for lowering of friction in large human joints by exogenous hyaluronic acid, the physical phenomenon standing behind these results has not been clarified yet. This leads to large dispersion in effectiveness and duration in action of viscosupplementation as a treatment for osteoarthritis and; subsequently, to disparity between the view of practitioners and recent procedures questioning or disregarding the efficiency of hyaluronic acid injections. In this study, the changes in friction between intact porcine cartilage and glass plate during reciprocating sliding tests were observed to better understand interaction between hyaluronic acid and synovial fluid components. Contact was lubricated with protein solutions both with and without addition of hyaluronic acid. The effectiveness of proteins and influence of hyaluronic acid on friction are discussed.
Czech name
—
Czech description
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Project
<a href="/en/project/LTAUSA17150" target="_blank" >LTAUSA17150: The effect of tribological processes on the durability of knee joint replacements</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Engineering Mechanics 2018
ISBN
978-80-86246-91-8
ISSN
—
e-ISSN
—
Number of pages
4
Pages from-to
709-712
Publisher name
Institute of Theretical and Applied Mechanics of the Czech Academy of Sciences
Place of publication
Praha
Event location
Svratka
Event date
May 14, 2018
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000465489800177

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