Experimental and computational modelling of flow of fibres in human airways

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F19%3APU132484" target="_blank" >RIV/00216305:26210/19:PU132484 - isvavai.cz</a>
Result on the web
<a href="https://www.liebertpub.com/doi/full/10.1089/jamp.2019.ab02.abstracts" target="_blank" >https://www.liebertpub.com/doi/full/10.1089/jamp.2019.ab02.abstracts</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Experimental and computational modelling of flow of fibres in human airways
Original language description
The ability of fibres to align with the flow has been identified as a reason for higher penetration of fibres into the lungs compared to spherical particles by many studies. However, prediction of the fate of inhaled fibres by computational methods is complicated due to the necessary mathematical apparatus and the lack of experimental data for validation. It is common to apply coefficients accounting for the preferential orientation of the fibre flowing through the airways. A new experimental rig has been built to visualize the flow of micron-sized fibres and record the angles of their rotation upstream and downstream of a single bifurcation. The recorded angles are statistically analysed and improved coefficients of fibre orientation will be calculated. The experimental rig consists of a dielectrophoretic classifier of fibres, the model of human trachea and first bronchi, a breathing simulator and a high-speed camera with appropriate illumination. These experiments are supplemented with computational
Czech name
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Czech description
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Project
<a href="/en/project/GA18-25618S" target="_blank" >GA18-25618S: Research of the effect of the non-stationary flow on the transport of fibers in successively bifurcating mini-channels</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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