The orientations of rigid glass fibres in turbulent flows inside a replica of human airways

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F23%3APU150017" target="_blank" >RIV/00216305:26210/23:PU150017 - isvavai.cz</a>
Result on the web
<a href="http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2023.pdf" target="_blank" >http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2023.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The orientations of rigid glass fibres in turbulent flows inside a replica of human airways
Original language description
The inhalation of fibers has long been recognized for its potential to induce a range of health-related concerns, primarily stemming from their ability to deeply penetrate the lower regions of the human respiratory system (Aust et al. 2011). However, instead of merely perceiving this behavior as a source of health risks, it presents an intriguing opportunity for the targeted delivery of therapeutic agents to the alveoli. This prospect not only captivates with its potential benefits but also holds significant commercial promise. Addressing this challenge, partly due to the limitations of our existing mathematical and computational models, which struggle to accurately predict the delivered dose for individual patients, and advancing our understanding of fiber dynamics in turbulent flows, this contribution introduces new data acquired within a replica of the human trachea and the first airway bifurcation. The measurements were performed under realistic inhalation conditions.
Czech name
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Czech description
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Project
<a href="/en/project/GA22-20357S" target="_blank" >GA22-20357S: Measurement and computational simulation of transport of fibrous aerosols in high velocity gradient flow and interaction of fibres with a wall</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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