Impact of inspiration flow resistance of nebulizer on spontaneous breathing pattern and its effect on regional lung deposition

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F23%3APU150047" target="_blank" >RIV/00216305:26210/23:PU150047 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Impact of inspiration flow resistance of nebulizer on spontaneous breathing pattern and its effect on regional lung deposition
Original language description
Usually, the inspiration flow resistance is discussed in the context of dry powder inhalers. However, can it be important also in the case of nebulizers? The nebulizers are commonly used with spontaneous breathing. There are no studies dealing with the differences in spontaneous breathing caused by the pressure drop of nebulizers. Within this study, we measured the spontaneous breathing of 10 male subjects while they used a nebulizer Pari LC Sprint Star and during the breathing without any nebulizer. The breath recordings were performed by a spirometer SpiroSonic SMART. The flow rate vs. time breathing profiles were recorded. The time scale was normalized in each breathing cycle. The flow rate in each normalized time step was averaged through the recorded cycles and subsequently through the subjects. A significant difference was detected between the breathing profile with and without nebulizer. In the case of the nebulizer usage, the peak inspiration flow rate was significantly lower, and the average
Czech name
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Czech description
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Project
<a href="/en/project/GA22-20357S" target="_blank" >GA22-20357S: Measurement and computational simulation of transport of fibrous aerosols in high velocity gradient flow and interaction of fibres with a wall</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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