Cell toxicity and preparation of streptavidin-modified iron nanoparticles and glutathione-modified cadmium-based quantum dots

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F10%3APU88630" target="_blank" >RIV/00216305:26220/10:PU88630 - isvavai.cz</a>

Alternative codes found

RIV/62157124:16370/10:00002667

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Cell toxicity and preparation of streptavidin-modified iron nanoparticles and glutathione-modified cadmium-based quantum dots

Original language description

This paper is focused on the investigation of conjugate nanostructures consisting of superparamagnetic nanoparticles (NPs) and CdSe/CdS quantum dots (QDs) with core/shell structure. In the first step, we prepared streptavidin (STP) conjugated Fe2O3 magnetic particles. The next stage was preparation of QDs using method based on surface modification of hydrophobic core/shell CdSe/CdS with biotinylated glutathione. Glutathione (GSH) belongs to the most abundant peptides in organisms maintaining redox status, which, from the particle point of view, makes the QDs water-soluble and stabilized in aqueous solution. Biotin molecule is known for its excellent affinity to streptavidin and hence allows the conjugation of both nanostructures (magnetic and light-emitting). We tested the influence of both prepared nanostructures on growth and viability of fibroblasts and BY-2 tobacco cells, respectively. NPs-STP and QDs-GSH may not pose a threat to cells, but non-modified nanoparticles and QDs withou

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

JB - Sensors, detecting elements, measurement and regulation

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Procedia Engineering

ISSN

1877-7058

e-ISSN

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Volume of the periodical

2010

Issue of the periodical within the volume

5

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

4

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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