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Synthesis and modification of quantum dots for medical applications

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F11%3APU95488" target="_blank" >RIV/00216305:26220/11:PU95488 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Synthesis and modification of quantum dots for medical applications

  • Original language description

    There is a growing interest in using semiconductor quantum dots (QDs) as optical labels for biosensing events. The size-controlled fluorescence properties of QDs, the high fluorescence quantum yields of QDs and their stability against photobleaching makes QDs superior optical labels for multiplex analysis. In this paper, biotin-conjugated glutathione (B-GSH) was synthesized using peptide bonding of the biotin carboxy group and amino group of the glutamic acid to create an alternative coating for CdTe QDs. This type of coating combines the functionality of biotin with the fluorescent properties of quantum dots to create a specific, high affinity fluorescent probe able to react with avidin, streptavidin and/or neutravidin. Biotin-funcionalized glutathione-coated QDs were prepared by a facile one step reduction route using Na2TeO3 as the Te source in an aqueous environment. The synthesis parameters of this simple and rapid approach, including the reaction temperature and time, the pH of t

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    JB - Sensors, detecting elements, measurement and regulation

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    NANOCON 2011 - sborník příspěvků

  • ISBN

    978-80-87294-23-9

  • ISSN

  • e-ISSN

  • Number of pages

    6

  • Pages from-to

    1-6

  • Publisher name

    TANGER spol. s r.o.

  • Place of publication

    Neuveden

  • Event location

    Brno

  • Event date

    Sep 21, 2011

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article