Comparison of gold nanostructured electrode and flat gold electrode on doxorubicin measurements

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F13%3APU105471" target="_blank" >RIV/00216305:26220/13:PU105471 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Comparison of gold nanostructured electrode and flat gold electrode on doxorubicin measurements
Original language description
Doxorubicin is a planar aromatic molecule and it is commonly used in cancer chemotherapy. In this study, we compared nanostructured electrodes with gold nanocolumns and flat gold electrodes by measurements with doxorubicin. Nanostructured electrodes were fabricated by electrochemical anodic oxidation when the aluminium layer was transformed to the porous alumina layer. Then gold material was deposited into the pores. After removal of aluminium template the nanostructured surface made of ordered gold nanocolumns on metal underlay was obtained. Flat gold electrodes were fabricated by evaporation of gold layer to the silicon substrate. After that, all electrodes were characterized by electrochemical impedance spectroscopy and then the detection of doxorubicin was studied by differential pulse voltammetry. According to the impedance spectroscopy measurements a bigger electroactive area for nanostructured electrodes was proved. The gold nanocolumns have been found as a significant factor in increasing of electrodes active area. This fact is very important for sensors sensitivity. Fabricated electrodes were successfully used for determination of doxorubicin. Doxorubicin oxidation peak was observed at a potential - 0.6 V.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Conference Proceedings 5th International Conference NANOCON 2013
ISBN
978-80-87294-47-5
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
215-219
Publisher name
Tanger, Ltd.
Place of publication
Ostrava
Event location
Brno
Event date
Oct 16, 2013
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000352070900036

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