Conjugation Bovine Serum Albumine with CdTe Quantum Dots

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F13%3APU105909" target="_blank" >RIV/00216305:26220/13:PU105909 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Conjugation Bovine Serum Albumine with CdTe Quantum Dots
Original language description
There is a growing interest in using semiconductor quantum dots (QDs) as optical labels for biosensing events. QDs have been linked with bio-recognition molecules such as proteins, peptides and nucleic acids, and have been successfully used in biologicaland medical fields such as immunoassay, DNA hybridization, cell imaging and potential photodynamic therapy. In this paper, the interaction between bovine serum albumin (BSA) and water soluble CdTe QDs modified with different ligands (3-mercaptoacetic acid, thioglycolic acid and glutathione) was studied using the fluorescence spectroscopy. It was found that the presence of QDs led to a strong quenching effect of BSA, which could be explained by a covalent interaction between the protein and the quencher, demonstrating the formation of QDs-BSA bioconjugates.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Conference Proceedings 5th International Conference NANOCON 2013
ISBN
978-80-87294-47-5
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
566-571
Publisher name
Tanger, Ltd.
Place of publication
Ostrava
Event location
Brno
Event date
Oct 16, 2013
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000352070900100

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