Evaluation of an Active Lung Simulator for Aerosol Inhalation Test Replacement

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F17%3APU124529" target="_blank" >RIV/00216305:26220/17:PU124529 - isvavai.cz</a>
Result on the web
<a href="http://www.altex.ch/altex-proceedings/wc-10-seattle" target="_blank" >http://www.altex.ch/altex-proceedings/wc-10-seattle</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Evaluation of an Active Lung Simulator for Aerosol Inhalation Test Replacement
Original language description
Aerosols are a ubiquitous part of the surrounding environment. Airborne particles may be produced by intention, as several spray-based cosmetics, but are not intended to be inhaled. The number of deposited particles in the lung tissue can only be estimated using mathematical models or simplified organ models. However, the question of actually deposited particles remains. The presented active lung simulator, i-Lung, has been designed to enable active inand exhalation and live measurement of environmental aerosols with a particle size distribution of 0.2 μm - 40 μm, representing respirable and inhalable aerosols. The i-Lung simulates an active spontaneously breathing human lung by changing the pressure within the housing of the different applicable lung equivalents as Latex bags or porcine lungs. An extracorporeal perfusion circuit, based on human lung transplantation techniques, is developed alongside and is supposed to nourish porcine lungs, taken from the slaughtering process.
Czech name
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Czech description
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Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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