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Contributions of basic, preclinical and clinical research to the application of induced electrical currents in the indications of rehabilitation and physical medicine

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F19%3APU144150" target="_blank" >RIV/00216305:26220/19:PU144150 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.prolekare.cz/casopisy/rehabilitace-fyzikalni-lekarstvi/2019-4-25/prinosy-zakladniho-preklinickeho-a-klinickeho-vyzkumu-k-uplatneni-indukovanych-elektrickych-proudu-v-indikacich-rehabilitacni-a-fyzikalni-mediciny-122203" target="_blank" >https://www.prolekare.cz/casopisy/rehabilitace-fyzikalni-lekarstvi/2019-4-25/prinosy-zakladniho-preklinickeho-a-klinickeho-vyzkumu-k-uplatneni-indukovanych-elektrickych-proudu-v-indikacich-rehabilitacni-a-fyzikalni-mediciny-122203</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Contributions of basic, preclinical and clinical research to the application of induced electrical currents in the indications of rehabilitation and physical medicine

  • Original language description

    The application of induced electric currents is increasingly used in contemporary rehabilitation and physical medicine. The induced electric currents are generated by a time-varying magnetic field and are apparently the only or at least a major biologi-cally active factor in the action of low-frequency electromagnetic fields. In addition to the “classical” pulse magnetotherapy, which provides the smallest densities of induced electric currents (usually thou-sandths to hundredths of A/m2), so-called distance or non-contact electrotherapy is increasingly popu-lar, but rather known under the names contactless electrotherapy, electrodeless therapy, inductively coupled electromagnetic field therapy, high-induction electromagnetic field therapy, etc., which typically operates at higher current densities of pulse-induced electrical currents in the order of tenths to A/m2. High-induction magnetic stimulation with perceptual and muscular motor effects, which provides current density of tens to hundreds of A/m2 in treated tissues, is also a significant development. In this work, we first investigated the effect of induced electric currents on sensory neurons responsible for the transmission of stimuli of various modalities, including those associated with nociception. In these cells, bradykinin modeled inflammation accompanied by increased calcium ion concentration in the intracellular space. We have demonstrated the influence of distance electrotherapy and high induction magnetic stimulation on the reduction of calcium concentration in the cell as well as on the slower onset and decrease of bradykinin-induced calcium wave. However, induced electrical current pulses produced by high induction magnetic stimulation increased spontaneous neuro-neuro-nal activity of primary afferent sensory cells without the presence of bradykinin inflammatory mediator. Further research was focused on the study of the behavior of endothelial cells, important in terms of angiogenesis, under the in

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database

  • CEP classification

  • OECD FORD branch

    20601 - Medical engineering

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Rehabilitace a Fyzikalni Lekarstvi

  • ISSN

    1211-2658

  • e-ISSN

  • Volume of the periodical

    2019

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    17

  • Pages from-to

    174-190

  • UT code for WoS article

  • EID of the result in the Scopus database

    2-s2.0-85090331555