Integrated Digital System for Long-Term Behavioral Tracking and Adaptive Electrical Brain Stimulation in Humans with Epilepsy

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F21%3APU144334" target="_blank" >RIV/00216305:26220/21:PU144334 - isvavai.cz</a>
Result on the web
<a href="https://cms.aesnet.org/abstractslisting/automated-sleep-classification-and-brain-stimulation-with-implantable-devices" target="_blank" >https://cms.aesnet.org/abstractslisting/automated-sleep-classification-and-brain-stimulation-with-implantable-devices</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Integrated Digital System for Long-Term Behavioral Tracking and Adaptive Electrical Brain Stimulation in Humans with Epilepsy
Original language description
Rationale: Electrical stimulation of the brain (ESB) is used in FDA-approved approaches for patients with drug resistant epilepsy (DRE), but current neuromodulatory approaches are largely palliative, difficult to optimize, and do not target psychiatric or cognitive comorbidities. We developed and implemented a digital health system for long-term tracking of interictal epileptiform activity, seizures, behavior, cognition, and mood comorbidities to improve the management of patients with DRE by streaming data from implanted and wearable devices, patient reported measures of sleep, cognition, and mood. Real-time analytics provides accurate seizure diaries, interictal epileptiform spike rates, dense behavioral tracking, and automated patient specific adaptive stimulation. Methods: Pre-clinical testing was completed in 13 pet and research canines with epilepsy implanted with the investigational Medtronic Summit RC+STM system (bilateral hippocampus & anterior nucleus of the thalamus), with wireless connect
Czech name
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Czech description
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Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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