Effects of the administration of different buffered balanced crystalloid solutions on acid-base and electrolyte status in dogs with gastric dilation-volvulus syndrome: a randomized clinical trial
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F22%3APU142400" target="_blank" >RIV/00216305:26220/22:PU142400 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16170/21:43879214
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S1938973621001033" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1938973621001033</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.tcam.2021.100613" target="_blank" >10.1016/j.tcam.2021.100613</a>
Alternative languages
Result language
angličtina
Original language name
Effects of the administration of different buffered balanced crystalloid solutions on acid-base and electrolyte status in dogs with gastric dilation-volvulus syndrome: a randomized clinical trial
Original language description
Objective: To investigate the effect of three different buffered balanced crystalloid solutions on acid–base status and electrolyte concentrations in dogs with gastric dilation–volvulus (GDV) syndrome. Methods: The study design was a prospective, randomized clinical trial of 40 dogs. The dogs were randomly assigned to one of three groups according to the fluid used: Hartmann’s solution (H), Plasmalyte (PL), and Ringerfundin (RF). Hemoglobin, albumin, lactate, electrolyte, and acid–base parameters were determined before fluid administration (T0) and at the end of surgery (T1). Results were assessed by one-way ANOVA, Fisher’s exact test, the Wilcoxon signed-rank test, the Kruskal–Wallis test, and a linear mixed-effect regression model. A significance level of 0.05 was used in all analyses. Results: Bicarbonate and base excess (BE) levels increased and chloride concentration decreased in the PL group; in contrast, strong ion difference apparent (SIDapp) decreased and chloride concentration increased in the RF group. The mixed-effect model confirmed a significant interaction between the type of solution and time on the changes in bicarbonate, BE, anion gap (AG), SIDapp, and chloride levels. Clinical significance: Significantly different effects in acid–base parameters were observed in dogs after intravenous administration of H, PL, and RF. However, clinical significance of these changes is lacking, requiring further investigation in a larger randomized controlled clinical trial.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
TOP COMPANION ANIM M
ISSN
1938-9736
e-ISSN
1946-9837
Volume of the periodical
46
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
1-10
UT code for WoS article
000740309000014
EID of the result in the Scopus database
2-s2.0-85121133281