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Clinical presentation and pulmonary function tests in post-acute COVID-19 patients

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F22%3APU145499" target="_blank" >RIV/00216305:26220/22:PU145499 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/23:00130052 RIV/61989592:15110/23:73613883 RIV/00098892:_____/23:10158102 RIV/65269705:_____/23:00076398

  • Result on the web

    <a href="https://pubmed.ncbi.nlm.nih.gov/36128850/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/36128850/</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2022.039" target="_blank" >10.5507/bp.2022.039</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Clinical presentation and pulmonary function tests in post-acute COVID-19 patients

  • Original language description

    Aims. The study analysed post-acute COVID-19 symptoms and the pulmonary function test (PFT) results in patients surviving the native strain of the virus. Methods. The study was prospective; the inclusion criteria were positive PCR test for SARS-CoV-2 and age 18-100. Exclusion criteria were active respiratory infection, known or suspicious pre-existing pulmonary disease, cardiac failure,recent or acute pulmonary embolism, anaemia, and neuromuscular diseases. The recruitment period was 1st March 2020 – 25th December 2020. The initial examination was performed 4–12 weeks after the disease onset. All subjects underwent physical examination, anamnesis, chest x-ray and PFT. Results. The study involved 785 subjects (345 male) mean age 53.8 (SD 14.6). The disease severity groups were: mild (G1), moderate (G2) and severe/critical (G3). Anosmia was present in the acute disease phase in 45.2% of G1 patients, but only in 4.5% of G3 patients. Dyspnoea occurred frequently in more severe groups (40%, 51.8% and 63.7% for G1, G2 and G3 respectively), while cough and fatigue showed no relationship to disease severity. Females were more likely to experience persistent symptoms. PFT results were significantly decreased in more severe groups compared to the mild COVID-19 patients, diffusing capacity was 86.3%, 79% and 68% of predicted values in G1, G2 and G3 respectively. Conclusion. Anosmia during the acute phase was associated with mild disease, persisting dyspnoea was more frequent after more severe COVID-19. Females tended to have persisting symptoms in post-acute phase more frequently. PFT results showed decrease with disease severity.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30203 - Respiratory systems

Result continuities

  • Project

    <a href="/en/project/VI04000039" target="_blank" >VI04000039: Early COVID-19 infection detection system for the safety of vulnerable groups using artificial intelligence</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    BIOMEDICAL PAPERS-OLOMOUC

  • ISSN

    1213-8118

  • e-ISSN

    1804-7521

  • Volume of the periodical

    166

  • Issue of the periodical within the volume

    XX

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    7

  • Pages from-to

    1-7

  • UT code for WoS article

    000863250600001

  • EID of the result in the Scopus database