Exercise-based Predictors of Late Recurrence of Atrial Fibrillation After Catheter Ablation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F22%3APU146904" target="_blank" >RIV/00216305:26220/22:PU146904 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Exercise-based Predictors of Late Recurrence of Atrial Fibrillation After Catheter Ablation

Original language description

Freedom from atrial fibrillation at 1 year is estimated to be between 55–80 % of patients undergoing catheter ablation. A significant number of them would require repeat procedures due to recurrent AF. Patients at higher risk for developing recurrent AF could benefit from different ablation strategies and post-ablation rhythm control therapy. We aim to identify the exercise-based risk factors associated with the first recurrence of AF between 3 and 36 months following the ablation. Patients (n=98, 69.4 % men) referred for catheter ablation of paroxysmal AF underwent simultaneous arm ergometry, exercise echocardiography and invasive left atrial pressure measurements. After the index ablation procedure, follow-up visits were scheduled at 1 up to 36 months. The observed freedom from AF recurrence during the follow-up was 81 %. Multivariable-adjusted Cox regression revealed the peak VO2 as the most significant predictor of late AF reccurence (hazard ratio 0.53, p<0.005). Among analyzed parameters, the lowest prediction error was achieved by including left atrial volume index, left atrial pressure and peak VO2 into age and sex adjusted Cox model (AIC=132.02, C-statistics=0.83). Presence of either decreased exercise capacity or elevated left atrial pressure is able to identify patients with potentially impaired left atrial function and different clinical outcome after conventional pulmonary vein isolation.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

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OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Computing in Cardiology 2022

ISBN

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ISSN

2325-887X

e-ISSN

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Number of pages

4

Pages from-to

1-4

Publisher name

Computing in Cardiology 2022

Place of publication

Tampere

Event location

Tampere, Finsko

Event date

Sep 3, 2022

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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