T1 mapping of myocardium in rats using self-gated golden-angle acquisition

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F23%3APU149041" target="_blank" >RIV/00216305:26220/23:PU149041 - isvavai.cz</a>
Alternative codes found
RIV/68081731:_____/24:00579323 RIV/00216224:14110/24:00135211 RIV/00159816:_____/23:00079732
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/mrm.29846" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/mrm.29846</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/mrm.29846" target="_blank" >10.1002/mrm.29846</a>

Result language
angličtina
Original language name
T1 mapping of myocardium in rats using self-gated golden-angle acquisition
Original language description
PurposeThe aim of this study is to design a method of myocardial T1 quantification in small laboratory animals and to investigate the effects of spatiotemporal regularization and the needed acquisition duration.MethodsWe propose a compressed-sensing approach to T1 quantification based on self-gated inversion-recovery radial two/three-dimensional (2D/3D) golden-angle stack-of-stars acquisition with image reconstruction performed using total-variation spatiotemporal regularization. The method was tested on a phantom and on a healthy rat, as well as on rats in a small myocardium-remodeling study.ResultsThe results showed a good match of the T1 estimates with the results obtained using the ground-truth method on a phantom and with the literature values for rats myocardium. The proposed 2D and 3D methods showed significant differences between normal and remodeling myocardium groups for acquisition lengths down to approximately 5 and 15 min, respectively.ConclusionsA new 2D and 3D method for quantification of myocardial T1 in rats was proposed. We have shown the capability of both techniques to distinguish between normal and remodeling myocardial tissue. We have shown the effects of image-reconstruction regularization weights and acquisition length on the T1 estimates.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20601 - Medical engineering

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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