Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F24%3APU151868" target="_blank" >RIV/00216305:26220/24:PU151868 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1109/TSP63128.2024.10605914" target="_blank" >https://doi.org/10.1109/TSP63128.2024.10605914</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/TSP63128.2024.10605914" target="_blank" >10.1109/TSP63128.2024.10605914</a>

Result language

angličtina

Original language name

Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication

Original language description

Hypokinetic dysarthria (HD), prevalent in Parkin-son's disease (PD), is characterized by reduced motor movement, leading to speech and voice impairments. The effectiveness of dopamine therapy varies, and symptoms may change over time. To explore the HD in patients on medication, we conducted hierarchical clustering to categorize 83 PD patients using the acoustic features extracted from recorded text reading, sustained phonation, and diadochokinetic task. We then compared these clusters to a group of 44 healthy controls. Regardless of the medication dosage and PD duration, patients displayed three distinct speech profiles: articulatory; respiratory-prosodic; and another more complex/severe regarding the number of HD do-mains affected. The newly identified profiles exhibit distinctions from previously defined speech subtypes in de novo PD patients. No differences in clinical scores were observed among the newly identified profiles, suggesting uniformity in clinical presentation despite distinct speech characteristics.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

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OECD FORD branch

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Project

<a href="/en/project/LX22NPO5107" target="_blank" >LX22NPO5107: National institute for Neurological Research</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

2024 47th International Conference on Telecommunications and Signal Processing (TSP)

ISBN

979-8-3503-6559-7

ISSN

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e-ISSN

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Number of pages

4

Pages from-to

270-273

Publisher name

IEEE

Place of publication

neuveden

Event location

Prague

Event date

Jul 10, 2024

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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