Determination of ionic concentration in microfluidics using electrical methods

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F26%3A0197953" target="_blank" >RIV/00216305:26220/26:0197953 - isvavai.cz</a>
Alternative codes found
RIV/62156489:43210/25:43927042
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0165993624005983?via=ihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0165993624005983?via=ihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.sna.2025.116719" target="_blank" >10.1016/j.sna.2025.116719</a>

Result language
angličtina
Original language name
Determination of ionic concentration in microfluidics using electrical methods
Original language description
Microfluidic systems are essential in various scientific and engineering applications, especially in biochemical analysis, medical diagnostics, and pharmaceutical research. Accurate monitoring and control of ionic concentration within these systems are essential for achieving high efficiency and specificity in their applications. This study investigates using van der Pauw (vdP) structures and 4-probe line methods, adapted from semiconductor technology, to measure ionic concentrations in microfluidic channels. These methods offer precise, real-time monitoring without requiring additional fabrication steps or specialized electrode materials. We fabricated microfluidic chips with dual deep reactive ion etching and anodic bonding. These chips, integrated into an automated system, were tested for KCl concentrations (0.1–4 M) across various channel depths (9.55 ± 0.23) µm, (22.37 ± 0.41) µm, and (82.26 ± 1.56) µm. Electrical measurements showed the vdP method provides higher accuracy and lower standard deviation than the 4-probe line method. Our findings demonstrate the potential for integrating vdP structures into complex microfluidic systems for precise, real-time monitoring of ionic concentrations, enhancing the functionality and reliability of microfluidic devices.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry

Project
<a href="/en/project/EF16_025%2F0007314" target="_blank" >EF16_025/0007314: Multidisciplinary research to increase application potential of nanomaterials in agricultural practice</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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