Detection of Heavy Metal Contamination by Vibrational Spectroscopy: A Combined Theoretical and Experimental Study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F26%3A0199132" target="_blank" >RIV/00216305:26220/26:0199132 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.13164/eeict.2025.195" target="_blank" >http://dx.doi.org/10.13164/eeict.2025.195</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.13164/eeict.2025.195" target="_blank" >10.13164/eeict.2025.195</a>
Alternative languages
Result language
angličtina
Original language name
Detection of Heavy Metal Contamination by Vibrational Spectroscopy: A Combined Theoretical and Experimental Study
Original language description
Heavy metal infiltration into connective tissues remains a notable yet under-explored issue in biomaterials research. In this study, we employed Fourier Transform Infrared (FTIR) spectroscopy to investigate potential mercury-induced changes in dentin, with an emphasis on the attenuation of thiol (–SH) vibrational signatures as a key indicator. High-resolution spectra, combined with chemometric preprocessing, enabled the detection of subtle perturbations in sulfur-containing amino acid residues. A reduction in thiol band intensity tentatively suggests mercury interactions with sulfhydryl groups, implying possible disruptions in protein conformation and the dentin organic matrix. Small but consistent shifts in amide I and II regions further point to collateral effects on dentinal proteins. To minimize confounding factors, we utilized selective reference spectra and limited elemental mapping, supporting the specificity of these observed alterations to localized mercury presence. While the initial results indicate a correlation between mercury exposure and diminished thiol peaks, additional data and systematic validation are needed to confirm these findings and clarify their broader clinical significance.
Czech name
—
Czech description
—
Classification
Type
D - Article in proceedings
CEP classification
—
OECD FORD branch
20200 - Electrical engineering, Electronic engineering, Information engineering
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Proceedings II of the Conference Student Eeict
ISBN
9788021463202
ISSN
—
e-ISSN
2788-1334
Number of pages
5
Pages from-to
195-199
Publisher name
Brno University of Technology
Place of publication
—
Event location
Brno
Event date
Apr 29, 2025
Type of event by nationality
CST - Celostátní akce
UT code for WoS article
—