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SoluProt: prediction of soluble protein expression in Escherichia coli

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26230%2F21%3APR36230" target="_blank" >RIV/00216305:26230/21:PR36230 - isvavai.cz</a>

  • Result on the web

    <a href="https://loschmidt.chemi.muni.cz/soluprot/" target="_blank" >https://loschmidt.chemi.muni.cz/soluprot/</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    SoluProt: prediction of soluble protein expression in Escherichia coli

  • Original language description

    A new tool for sequence-based prediction of soluble protein expression in Escherichia coli, SoluProt, was created using the gradient boosting machine technique with the TargetTrack database as a training set. When evaluated against a balanced independent test set derived from the NESG database, SoluProts accuracy of 58.4% and AUC of 0.60 exceeded those of a suite of alternative solubility prediction tools. There is also evidence that it could significantly increase the success rate of experimental protein studies. SoluProt is freely available as a standalone program and a user-friendly webserver at https://loschmidt.chemi.muni.cz/soluprot/.

  • Czech name

  • Czech description

Classification

  • Type

    R - Software

  • CEP classification

  • OECD FORD branch

    20206 - Computer hardware and architecture

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Internal product ID

    SoluProt

  • Technical parameters

    Pro informace o licenčních podmínkách prosím kontaktujte: Mgr. Radka Báčová, Výzkumné centrum informačních technologií, Fakulta informačních technologií VUT v Brně, Božetěchova 2, 612 66 Brno, 541 141 473.

  • Economical parameters

    SoluProt je poskytován jako nezisková webová služba pro vědeckou komunitu.

  • Owner IČO

    00216305

  • Owner name

    Vysoké učení technické v Brně