Unraveling Cognitive Impairments in Mental and Neurological Disorders: A Biomarker-Based Mapping Framework
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26230%2F26%3A0198383" target="_blank" >RIV/00216305:26230/26:0198383 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0149763425004270?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0149763425004270?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.neubiorev.2025.106426" target="_blank" >10.1016/j.neubiorev.2025.106426</a>
Alternative languages
Result language
angličtina
Original language name
Unraveling Cognitive Impairments in Mental and Neurological Disorders: A Biomarker-Based Mapping Framework
Original language description
This systematic review investigates the intricate relationships between cognitive skill impairments and mental and neurological disorders (MNDs) through neurophysiological, neurochemical, and connectivity-based biomarkers. The paper systematically maps the six primary cognitive domains, complex attention, learning and memory, language, executive function, social cognition, and perceptual-motor function, and their subdomains, as defined by the DSM-5, to 11 major MNDs, including schizophrenia, bipolar disorder, Alzheimer’s disease, and autism spectrum disorder. The study identifies critical biomarkers such as EEG band power, event-related potentials (ERPs), microstate dynamics, Connectivity measures, and neurotransmitter imbalances, elucidating their role in linking specific cognitive impairments with MNDs. Additionally, the paper introduces an interactive tool that allows researchers and clinicians to explore dynamic mappings among biomarkers, cognitive skills, and MNDs, facilitating tailored analyses and evidence-based decision-making. This comprehensive mapping advances our understanding of the neurobiological underpinnings of MNDs and underscores the potential of biomarker-based approaches for improving diagnostic precision and designing targeted therapeutic strategies.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Result continuities
Project
<a href="/en/project/GA24-10990S" target="_blank" >GA24-10990S: Hardware-Aware Machine Learning: From Automated Design to Innovative and Explainable Solutions</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuroscience and Biobehavioral Reviews
ISSN
0149-7634
e-ISSN
1873-7528
Volume of the periodical
180
Issue of the periodical within the volume
106426
Country of publishing house
GB - UNITED KINGDOM
Number of pages
28
Pages from-to
0-0
UT code for WoS article
001625710500001
EID of the result in the Scopus database
2-s2.0-105022185686