Determination of naturally-occuring alkaloids in feed by UPLC-MS/MS
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F13%3APU105794" target="_blank" >RIV/00216305:26310/13:PU105794 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Determination of naturally-occuring alkaloids in feed by UPLC-MS/MS
Original language description
Alkaloids, which are known as secondary metabolites, are produced by a large variety of organisms, including plants, fungi, bacteria and animals. Alkaloids are not crucial for the survival of the mentioned organisms, but for their protection. They are grouped by typical structural characteristics into large families such as pyrrolizidine alkaloids (PAs) comprising more than 350 individual heterocyclic compounds. As other alkaloids PAs can cause severe human and animal health problems. Intoxications caused by PAs are described by hepatotoxicity with tendency to hemorrhagic necrosis and veno-occlusion in liver, pneumotoxicity, carcinogenity, mutagenity, and genotoxicity [1]. Thus, there is a need for methods that allow to determinate these dangerous plant toxins. In this study, fast, reliable and sensitive approach is proposed allowing simultaneous screening, identification and quantification of PAs in feed samples. Selected PAs representatives, namely monocrotaline, senkirkine, senecion
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů