Fluorescence study of effect of hyaluronan addition to micelle solution of cetyltrimethylammonium bromide

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F15%3APU119542" target="_blank" >RIV/00216305:26310/15:PU119542 - isvavai.cz</a>
Result on the web
<a href="http://www.fch.vut.cz/media/sok/sbornik_prispevku_2015.pdf" target="_blank" >http://www.fch.vut.cz/media/sok/sbornik_prispevku_2015.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Fluorescence study of effect of hyaluronan addition to micelle solution of cetyltrimethylammonium bromide
Original language description
This study deals with the effect of hyaluronan addition on the micellar formation of cationic surfactant cetyltrimethylammonium bromide (CTAB) in aqueous solution. Hyaluronan as negatively charged polyelectrolyte can interact with cationic micelles via electrostatic interactions to form aggregates, which could be potential used for targeted drug delivery. The effect of hyaluronan addition to CTAB solution was study by fluorescence measurement of two fluorescence probes located in different regions of micelles – hydrophobic perylene, which is solubilized in hydrophobic interior and hydrophilic one, fluorescein, which is located on the surface of cationic micelles due to its anionic character. The excitation and emission spectra, intensity of fluorescence, steady-state anisotropy of fluorescence and lifetime of probes in the samples were measured. It is observed, that the addition of hyaluronan to micellar solution of CTAB affected structural changes of microenvironment near the molecules of both fluorescence probes, which are reflected at increasing values of fluorescence anisotropy simultaneously with increasing amount of hyaluronan in solutions.
Czech name
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Czech description
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Project
<a href="/en/project/LO1211" target="_blank" >LO1211: Materials Research Centre at FCH BUT- Sustainability and Development</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Studentská odborná konference Chemie je život 2015, Sborník příspěvků
ISBN
978-80-214-5290-9
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
244-250
Publisher name
Vysoké učení technické v Brně, Fakulta chemická, Purkyňova 464/118, 612 00 Brno
Place of publication
Brno
Event location
Brno
Event date
Dec 3, 2015
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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