Hydrogels based on cationic polyelectrolytes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F17%3APU124406" target="_blank" >RIV/00216305:26310/17:PU124406 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Hydrogels based on cationic polyelectrolytes
Original language description
The main aim of this work is laboratory preparation and characterization of hydrogels based on cationic polyelectrolytes. Cationic polyelectrolytes can interact with oppositely charged surfactants via electrostatic forces. Interactions between cationic polyelectrolytes and anionic surfactants can generate physical gels (under proper conditions such as temperature, pH, ionic strenght) and surfactants are able to form micellar structures suitable for solubilizing hydrophobic compounds in aqueous environment of the gel. Resulting materials are hydrogels which contain hydrophobic nanodomains so it is possible to use like porters in drug delivery in medicine, e.g. hydrophobic drugs for topical applications (wound healing and so on). The presence of hydrophobic nanodomains was tested by solubilization tests with the help of hydrophobic dyes (e.g. Oil red O, prodan). Mechanical properties of prepared materials were tested rheologically (in dependence of their composition). This work is focused on the preparation of gels from positively charged polysaccharides dextran hydrochloride and negatively charged surfactant sodium dodecyl sulphate.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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