Advanced Microrheological Techniques In The Research Of Hydrogels

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F17%3APU124781" target="_blank" >RIV/00216305:26310/17:PU124781 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Advanced Microrheological Techniques In The Research Of Hydrogels
Original language description
This work is focused on the use of advanced fluorescence correlation spectroscopy technique (FCS) in microrheological characterization of hydrogels. Hydrogels were prepared from negatively charged polymer (sodium hyaluronate) and oppositely charged surfactant (cetyltrimethylammonium bromide) in physiological environment. Low, medium and high molecular weight sodium hyaluronate was used. Our hydrogels contain more than 90 % of water and they are able to solubilize hydrophobic and hydrophilic species. These hydrogels contain hydrophobic nanodomains (nanocontainers) and can be promising materials for the use in many applications, e.g. in topical applications or local drug delivery systems. Main aim of this work is to study microrhelological behavior of these systems and usability of FCS technique in these systems. For microrheological FCS analysis were used fluorescently labelled particles. Optimum particle size was selected based on analysis of Newtonian glycerol solutions. The results of FCS hydrogel m
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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