Quantitative determination of the veterinary drug monensin in horse feed samples by square wave voltammetry (SWV) and direct infusion electrospray ionization tandem mass spectrometry (DI–ESI–MS/MS)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F18%3APU128221" target="_blank" >RIV/00216305:26310/18:PU128221 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1016/j.microc.2018.05.032" target="_blank" >https://doi.org/10.1016/j.microc.2018.05.032</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Quantitative determination of the veterinary drug monensin in horse feed samples by square wave voltammetry (SWV) and direct infusion electrospray ionization tandem mass spectrometry (DI–ESI–MS/MS)

Original language description

This paper presents for the first time the determination of monensin monosodium salt (MnzNa) by means of square wave voltammetry (SWV), cyclic voltammetry (CV), and, in parallel, direct infusion electrospray ionization tandem mass spectrometry (DI–ESI–MS/MS). The influence of various factors, such as pH, buffer composition, and SWV parameters on current response was studied. The best SWV signal was obtained at about -1.50 V versus an Ag/AgCl/KCl reference electrode in Britton–Robinson (B–R) buffer. Under optimal conditions, the SWV response of the renewable silver amalgam film electrode Hg(Ag)FE was linear over two MnzNa concentration ranges, from 7.5x10-8 to 5.0x10-7 mol L-1 and from 5.0x10-7 to 1.0x10-5 mol L-1. The limits of detection and quantification were 1.27x10-8 mol L-1 and 4.23x10-8 mol L-1, respectively. The applicability of the developed SWV method was investigated in the determination of MnzNa in horse feed by the standard addition method. CV was applied to understand the electrode mechanism of MnzNa. Finally, direct infusion electrospray ionization tandem mass spectrometry (DI–ESI–MS/MS) was used to determine MnzNa in horse feed samples by the external calibration method. The detector response was linear in the concentration range of 1.1x10-7 to 1.4x10-6 mol L-1. The obtained limits of detection and quantification were 3.4x10-8 mol L-1 and 1.1x10-7 mol L-1, respectively. Statistical analysis of MnzNa determination results from SWV and DI–ESI–MS/MS did not reveal any significant differences between them.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

<a href="/en/project/LO1211" target="_blank" >LO1211: Materials Research Centre at FCH BUT- Sustainability and Development</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

MICROCHEMICAL JOURNAL

ISSN

0026-265X

e-ISSN

1095-9149

Volume of the periodical

141

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

9

Pages from-to

220-228

UT code for WoS article

000439678200029

EID of the result in the Scopus database

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