Transport of a model diffusion probe in polyelectrolyte-surfactant hydrogels

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F19%3APU131932" target="_blank" >RIV/00216305:26310/19:PU131932 - isvavai.cz</a>

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0927775719301700" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0927775719301700</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.colsurfa.2019.04.042" target="_blank" >10.1016/j.colsurfa.2019.04.042</a>

Result language

angličtina

Original language name

Transport of a model diffusion probe in polyelectrolyte-surfactant hydrogels

Original language description

Interactions of biopolymeric electrolytes with oppositely charged surfactants can result in micelle-like nanocontainers capable to dissolve hydrophobic substances. These micelle-like nanostructures can solve problems with hydrophobic nature of pharmaceutically active substances and be potentially usable for medical applications. In this study, two types of hydrogels were prepared: 1) based on hyaluronan and cationic surfactant septonex (carbethoxypendecinium bromide) and 2) based on diethylaminoethyl dextran and sodium dodecylsulphate. Nile red as a dye diffusion probe was incorporated into hydrogel in their preparation and then its release into surfactant solution and physiological saline was monitored. The release of NR from hydrogels was characterized by the effective diffusion coefficients of NR and structural parameters of hydrogels. The diffusion of NR in hydrogels was dependent on the molecular weight of polyelectrolyte and the ratio between charges of polyelectrolyte and surfactant. In the case of lower ratios, a bigger part of NR was probably incorporated in “pearl necklace structure” which suppressed its mobility. The increase of concentration of surfactant was connected with higher content of NR in free micelles or micelle-like aggregates and the increase in the release of NR. The formation of bigger micelles based on NR and SDS (in comparison with micelles based on NR and septonex surfactant) resulted in their lower diffusivity.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10403 - Physical chemistry

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Colloids and Surfaces A: Physicochemical and Engineering Aspects

ISSN

0927-7757

e-ISSN

1873-4359

Volume of the periodical

573

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

7

Pages from-to

73-79

UT code for WoS article

000468418300009

EID of the result in the Scopus database

2-s2.0-85064835010